Autophagy is an intracellular self-degradative process to maintain cellular metabolism and homeostasis. Increasing studies have implicating deregulation of autophagy has been implicated in the pathogenesis of several ocular diseases, such as age-related macular degeneration, glaucoma, diabetic retinopathy. Our long-term goal is to study the function of autophagy in prevention of neuron cell damage and manipulate autophagy as a treatment against ocular neurodegeneration.

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